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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX12
All Species:
13.94
Human Site:
S486
Identified Species:
23.59
UniProt:
Q92771
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92771
NP_004391
950
106006
S486
K
Q
N
P
N
T
Q
S
L
S
Q
T
G
M
E
Chimpanzee
Pan troglodytes
XP_520821
925
103112
S486
K
Q
N
P
N
T
Q
S
L
S
Q
T
G
T
E
Rhesus Macaque
Macaca mulatta
XP_001114477
931
104280
S467
K
Q
N
P
N
T
Q
S
L
S
Q
T
G
T
E
Dog
Lupus familis
XP_543872
907
102087
L468
Q
N
P
N
T
Q
S
L
S
Q
T
G
T
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6AXC6
880
98710
S438
K
Q
N
P
T
T
Q
S
L
S
Q
T
G
S
E
Rat
Rattus norvegicus
XP_001070646
845
94905
Q416
N
D
F
L
F
Q
S
Q
V
D
N
I
N
L
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517598
930
104705
T498
N
T
Q
T
L
S
Q
T
G
T
E
L
K
T
I
Chicken
Gallus gallus
XP_416375
940
105739
V498
N
Q
N
P
S
C
Q
V
V
S
Q
T
G
T
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007320
890
100643
Q445
V
G
Q
N
P
N
T
Q
S
C
Q
T
G
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569898
861
96577
D441
E
G
D
F
F
N
I
D
L
C
E
L
L
D
F
Honey Bee
Apis mellifera
XP_001121183
769
88327
M373
L
Y
K
I
E
E
I
M
T
E
I
D
T
V
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792082
780
88384
N384
S
Q
I
S
R
K
L
N
G
F
V
E
R
Y
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22516
861
98787
K457
T
L
I
Q
F
I
V
K
N
F
K
K
I
G
Q
Red Bread Mold
Neurospora crassa
A7UXD4
1073
119198
A572
K
T
K
L
D
K
A
A
L
G
L
K
A
D
Q
Conservation
Percent
Protein Identity:
100
94.4
92.4
78.3
N.A.
72.3
67.7
N.A.
71.3
67.7
N.A.
57.2
N.A.
37.5
36.3
N.A.
45.4
Protein Similarity:
100
95.8
94.4
85.2
N.A.
80
76.2
N.A.
81.7
80.2
N.A.
73.4
N.A.
53.6
53.7
N.A.
61
P-Site Identity:
100
93.3
93.3
0
N.A.
86.6
0
N.A.
6.6
60
N.A.
26.6
N.A.
6.6
0
N.A.
6.6
P-Site Similarity:
100
93.3
93.3
6.6
N.A.
86.6
13.3
N.A.
33.3
73.3
N.A.
26.6
N.A.
26.6
6.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.2
25.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.5
43.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
8
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
15
0
0
0
0
0
% C
% Asp:
0
8
8
0
8
0
0
8
0
8
0
8
0
15
0
% D
% Glu:
8
0
0
0
8
8
0
0
0
8
15
8
0
8
43
% E
% Phe:
0
0
8
8
22
0
0
0
0
15
0
0
0
0
15
% F
% Gly:
0
15
0
0
0
0
0
0
15
8
0
8
43
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
15
8
0
8
15
0
0
0
8
8
8
0
8
% I
% Lys:
36
0
15
0
0
15
0
8
0
0
8
15
8
0
0
% K
% Leu:
8
8
0
15
8
0
8
8
43
0
8
15
8
8
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% M
% Asn:
22
8
36
15
22
15
0
8
8
0
8
0
8
0
8
% N
% Pro:
0
0
8
36
8
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
43
15
8
0
15
43
15
0
8
43
0
0
0
22
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
8
0
0
8
8
8
15
29
15
36
0
0
0
15
0
% S
% Thr:
8
15
0
8
15
29
8
8
8
8
8
43
15
29
0
% T
% Val:
8
0
0
0
0
0
8
8
15
0
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _